ACS Nano主编与生物材料牛人R. Langer的对话

2016-10-10新闻资讯

R. Langer


Robert S. Langer is one of 14 Institute Professors (the highest honor awarded to a faculty member) at the Massachusetts Institute of Technology (MIT).  Dr. Langer has written over 1,000 articles.  He also has more than 600 issued or pending patents worldwide. Dr. Langer’s patents have been licensed or sublicensed to over 200 pharmaceutical, chemical, biotechnology and medical device companies. He is the most cited engineer in history.
  
     He served as a member of the United States Food and Drug Administration’s SCIENCE Board, the FDA’s highest advisory board, from 1995 -- 2002 and as its Chairman from 1999-2002.
     Dr. Langer has received over 160 major awards including the 2006 United States National Medal of Science; the Charles Stark Draper Prize, considered the equivalent of the Nobel Prize for engineers and the 2008 Millennium Prize, the world’s largest technology prize.  He is the also the only engineer to receive the Gairdner Foundation International Award; 72 recipients of this award have subsequently received a Nobel Prize.  Among numerous other awards Langer has received are the Dickson Prize for Science (2002), Heinz Award for Technology, Economy and Employment (2003), the Harvey Prize (2003), the John Fritz Award (2003) (given previously to inventors such as Thomas Edison and Orville Wright), the General Motors Kettering Prize for Cancer Research (2004), the Dan David Prize in Materials Science (2005), the Albany Medical Center Prize in Medicine and Biomedical Research (2005), the largest prize in the U.S. for medical research, induction into the National Inventors Hall of Fame (2006), the Max Planck Research Award (2008) and the Prince of Asturias Award for Technical and Scientific Research (2008).  In 1998, he received the Lemelson-MIT prize, the world’s largest prize for invention for being “one of history’s most prolific inventors in medicine.”  In 1989 Dr. Langer was elected to the Institute of Medicine of the National Academy of Sciences, and in 1992 he was elected to both the National Academy of Engineering and to the National Academy of Sciences.  He is one of very few people ever elected to all three United States National Academies and the youngest in history (at age 43) to ever receive this distinction.
      Forbes Magazine (1999) and Bio World (1990) have named Dr. Langer as one of the 25 most important individuals in biotechnology in the world.  Discover Magazine (2002) named him as one of the 20 most important people in this area.  Forbes Magazine (2002) selected Dr. Langer as one of the 15 innovators world wide who will reinvent our future.  Time Magazine and CNN (2001) named Dr. Langer as one of the 100 most important people in America and one of the 18 top people in science or medicine in America (America’s Best).  Parade Magazine (2004) selected Dr. Langer as one of 6 “Heroes whose research may save your life.”  Dr. Langer has received honorary doctorates from Yale University, the ETH (Switzerland), the Technion (Israel), the Hebrew University of Jerusalem (Israel), the Universite Catholique de Louvain (Belgium), the University of Liverpool (England), the University of Nottingham (England), Albany Medical College, the Pennsylvania State University, Northwestern University and Uppsala University (Sweden).  He received his Bachelor’s Degree from Cornell University in 1970 and his Sc.D. from the Massachusetts Institute of Technology in 1974, both in Chemical Engineering.

 

罗伯特·S·兰格(Robert S. Langer):生于1948年8月29日出生于纽约州奥尔巴尼,美国麻省理工学院教授。他是前化学和生物医学工程“Germeshausen教授”,并且一直活跃在MIT的化学工程系和生物工程系。他还是哈佛-MIT健康科学技术分部(Harvard-MIT Division of Health Sciences and Technology)的一名教员。

他在生物技术领域,尤其是药物输送系统和组织工程领域享有很高的声望。他在麻省理工的实验室是世界最大的生物医学工程实验室,每年大约能获得600万美元的研究资助,实验室的研究人员已经超过100名。

他对医学和新出现的生物技术领域的贡献已经得到全世界的高度认可和尊重。他被认为是许多新技术的先锋开拓者,其中包括透皮给药系统(transdermal delivery systems,即贴布)。这个系统能够将药物或身体的提取分析物以不需要注射或其他入侵方法的方式穿过皮肤。他和他实验室的研究人员还在组织工程学领域取得了一些重要的进展,例如创造出血管工程肌肉组织(vascularized engineered musle tissue)和经改造的血管。

他持有超过550项已经通过申请或待审的专利,发表了超过900篇科学论文。他积极创业,先后参与创建了超过20个公司。兰格曾获得多个奖项,包括Charles Stark Draper奖、Lemelson-MIT奖和Albany医学中心医学与生物医学研究大奖。此外,他还是当选美国三大科学院院士(美国科学院、美国工程院和医学院)年纪最轻(43岁时)的人。

他还预测用新型生物材料制造的医疗器械也即将诞生。目前使用的大多数生物材料都是用于普通消费品生产的标准材料。比如,人工心脏所用的材料原来用于制造女士腰带。有些丰胸材料曾经被用作床垫填充物。

获奖成就:组织工程学和再生医学的先驱研究

百科:组织工程学是由美国国家科学基金委员会于1987年正式提出和确定的,是应用细胞生物学、生物材料和工程学的原理,研究开发用于修复或改善人体病损组织或器官的结构、功能的生物活性替代物的一门科学。

再生医学是通过研究机体的正常组织特征与功能、创伤修复与再生机制及干细胞分化机理,寻找有效的生物治疗方法,促进机体自我修复与再生,或构建新的组织与器官,以改善或恢复损伤组织和器官的功能的科学。